FDA Testing Finds Hormones in ORL Toothpaste

ORL Labs LLC, based in Scottsdale, Arizona, is recalling 51,762 units of its ORL Organic Oral Care toothpastes and mouthwashes nationwide. The Food and Drug Administration's sampling found progesterone, estradiol or dehydroepiandrosterone, known as DHEA, in the products, and the agency lists the cause as cross-contamination. None of the three hormones belongs in toothpaste.

Six products are covered, and three of them are children's versions. The lots include Bubblegum Kids natural toothpaste at 3,976 units, Cinnamint toothpaste at 7,202 units, Fresh Mint natural toothpaste at 19,247 units and Fresh Mint mouthwash at 12,081 units, with kids' mouthwash and a Cinnamint mouthwash completing the set. Affected lots carry expiration dates running from September 2026 through August 2028.

ORL initiated the recall on October 12, 2026, and the FDA classified it as Class II on November 6. A Class II classification means use of the product may cause temporary or medically reversible health consequences, and the probability of a serious health problem is remote. No illnesses have been reported, and the recall notice doesn't explain how the contamination happened.

This isn't the first time these products have drawn the FDA's attention. In December 2025, Signature Formulations, a manufacturer of ORL products, recalled ORL kids' bubblegum toothpaste and mouthwash over potential contamination with the same kind of hormones. In January 2026, the company received an FDA warning letter citing manufacturing violations, including inadequate separation of production areas to prevent cross-contamination. Signature also makes supplements that include bioidentical hormones.

The practical instruction is simple. Anyone holding one of the six products should stop using it and discard it or return it to the retailer, according to the recall coverage. The FDA's consumer line is 1-888-463-6332.

As of November 10, 2026, ORL's website said it was undergoing maintenance and had temporarily paused all orders. The company hasn't announced when sales will resume.